EC Number   |
Protein Variants |
Reference |
|---|
    3.5.4.19 | C109/C116 |
no measurable catalytic activity, not capable of binding Zn2+ |
726992 |
| 3.5.4.19 | C109A |
no measurable catalytic activity, not capable of binding Zn2+ |
726992 |
| 3.5.4.19 | C116A |
no measurable catalytic activity, still capable of binding Zn2+ |
726992 |
| 3.5.4.19 | C93A |
no measurable catalytic activity |
726992 |
| 3.5.4.19 | D92E |
180fold loss in catalytic efficiency (kcat/Km), decrease in Zn2+ content |
726992 |
| 3.5.4.19 | D94A |
no measurable catalytic activity, decrease in Zn2+ content |
726992 |
| 3.5.4.19 | D94E |
2300fold decrease in activity, decrease in Zn2+ content |
726992 |
| 3.5.4.19 | H110A |
500fold decrease in activity, no decrease in Zn2+ content |
726992 |
