EC Number   |
Protein Variants |
Reference |
|---|
   3.4.24.B16 | G115A |
slightly reduced activity |
680489 |
| 3.4.24.B16 | H120A |
oligonucleotide-directed mutagenesis, formation of the lasA5 allele, processing to a 20 kDa LasA-H120A protein and secretion to the medium occurs, but the mutant enzyme has no staphylolytic activity |
-, 651625 |
| 3.4.24.B16 | H94A |
mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity |
680489 |
| 3.4.24.B16 | I101A |
mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity |
680489 |
| 3.4.24.B16 | L92A |
mutation results in highly unstable protein that is susceptible to proteolytic degradation |
680489 |
| 3.4.24.B16 | N102A |
mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity |
680489 |
| 3.4.24.B16 | W95A |
mutation results in highly unstable protein that is susceptible to proteolytic degradation |
680489 |
