EC Number   |
Protein Variants |
Reference |
|---|
   3.4.22.45 | more |
a point mutation in the highly conserved FRNK box produces the HC-ProFINK protein that shows no sRNA binding |
718356 |
| 3.4.22.45 | K307E |
active in aphid transmission |
137295 |
| 3.4.22.45 | K307R |
active in aphid transmission |
137295 |
| 3.4.22.45 | C305S |
active in aphid transmission, similar to wild-type |
137295 |
| 3.4.22.45 | C649S |
active site mutant, no activity |
137288 |
| 3.4.22.45 | H722S |
active site mutant, no activity |
137288 |
| 3.4.22.45 | E396N |
affects symptom severity and viral pathogenicity |
713072 |
| 3.4.22.45 | F205L |
affects symptom severity and viral pathogenicity |
713072 |
| 3.4.22.45 | R180I |
affects symptom severity and viral pathogenicity |
713072 |
| 3.4.22.45 | more |
certain mutations introduced to the short, variable region of the enzyme increase accumulation of the enzyme and prolong the time which it remains effective in suppression of RNA silencing |
732407 |
