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Results 1 - 10 of 13 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19D22H mutant with no residual enzyme acitvity 707533
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19D320A mutant with no residual enzyme acitvity 707533
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19D320N mutant with no residual enzyme acitvity 707533
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H128L mutant enzyme exhibits a specific activity and Km for Gly-D-Phe comparable with that of the wild-type enzyme 647114
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H150A mutant with more than doubled Km-values 707533
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H150N mutant with more than doubled Km-values 707533
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H152L inactive mutant enzyme is expressed at the cell surface at equivalent levels to the wild-type, the mutant enzyme fails to bind to cilastatin-Sepharose in contrast to the wild-type enzyme 647114
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H198K inactive mutant enzyme is expressed at the cell surface at equivalent levels to the wild-type 647114
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H20L inactive mutant enzyme is expressed at the cell surface at equivalent levels to the wild-type 647114
Show all pathways known for 3.4.13.19Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.19H413K/H417K catalytic activity reduced to background levels. Animals carrying the mutant enzyme generate 1 embryo from 22 plugged females compared to 153 embryos from 19 females in wild-type. There is no difference in sperm count, morphology or motility after capacitation in mutant animals. While sperm from wild-type males readily binds to the zona pellucida of unfertilized eggs, sperm from homozygous mutant males shows background levels of binding 670357
Results 1 - 10 of 13 > >>