EC Number   |
Protein Variants |
Reference |
|---|
   3.4.11.24 | D3A/D262G |
site-directed mutagenesis, the mutant shows increased activity compared to the wild-type enzyme |
665735 |
| 3.4.11.24 | E131 |
site-directed mutagenesis, the mutant enzyme shows reduced activity compared to the wild-type enzyme |
664938 |
| 3.4.11.24 | E131D |
a general acid-base mutant, thermodynamic parameters for the reaction are similar to the wild-type enzyme, but the kcat of the mutant is 4fold reduced, while the activation energy is elevated compared to the wild-type enzyme |
686663 |
| 3.4.11.24 | E196A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
665735 |
| 3.4.11.24 | F221A |
site-directed mutagenesis, the mutant shows altered substrate specificity compared to the wild-type enzyme |
-, 663713 |
| 3.4.11.24 | F221G |
site-directed mutagenesis, the mutant shows altered substrate specificity compared to the wild-type enzyme |
-, 663713 |
| 3.4.11.24 | F221S |
site-directed mutagenesis, the mutant shows altered substrate specificity compared to the wild-type enzyme |
-, 663713 |
| 3.4.11.24 | more |
alteration of leucine aminopeptidase to phenylalanine aminopeptidase by site-directed mutagenesis |
-, 663713 |
| 3.4.11.24 | more |
construction of chimeric enzymes from the enzymes of Streptomyces griseus and Streptomyces septatus by DNA in vivo shuffling and site-directed mutagenesis for calcium activation and binding studies, overview |
665735 |
| 3.4.11.24 | S502C |
mutant without aminopeptidase activity but with peptide synthesis activity |
-, 708107 |
