   2.8.4.2 | more |
gene deletion mutants of isoforms ArsC1 and ArsC2 show similar resistance levels to As(V) as wild-type. the ArsC1/ArsC2 double mutant strain is very sensitive to arsenate and shows resistance levels, which are 2030 times lower. Only plasmids containing either the arsC1 or the arsC2 gene are able to complement the arsenate reductase activity. When the single cysteine in the arsC1 and the arsC2 genes is mutated to a serine, the complementation is lost. Removing arsC1, arsC2, or both genes had no effect on the resistance against As(III), and resistance levels equivalent to those for wild type are obtained |
698899 |
