EC Number   |
Protein Variants |
Reference |
|---|
    2.7.7.41 | C102Y |
mutation is the molecular basis for the inositol excretion phenotype |
643327 |
| 2.7.7.41 | C1226T/C1227T/P363S |
construction of loss-of-function mutation in CDP-DG synthase in Schizosaccharomyces japonicus bbl1 mutant cells, the mutation triggers abnormal lipid droplet biogenesis and triacylglycerol accumulation. The P363S mutation in the Cds1 enzyme leads to a reduction in its CDP-DG synthase activity and potential shunting of a bulk of cellular phosphatidate into triacylglycerol biosynthesis through the DG pathway. The cds1bbl1 mutation is recessive, since introduction of the wild-type gene as an extra copy fully rescues the phenotype of bbl1 cells. Mutant bbl1 phenotype, overview |
-, 739033 |
| 2.7.7.41 | D220A |
site-directed mutagenesis of TAM41, catalytically inactive mutant |
738000 |
| 2.7.7.41 | F240A |
the mutant retains about 47% of wild type activity |
-, 762488 |
| 2.7.7.41 | K156A |
the mutant retains 6.81% of wild type activity |
-, 762488 |
| 2.7.7.41 | K183A |
the mutant enzyme is almost inactive |
-, 762488 |
| 2.7.7.41 | more |
generation of a conditional CDS knockout in the bloodstream form parasite, phenotype, overview |
-, 741020 |
| 2.7.7.41 | more |
generation of a T-DNA insertion (in the 5' untranslated region) mutant of CDS1, the cds1cds2 double mutant is seedling lethal, phenotypes, overview. The seedling-lethal phenotype of cds1cds2 double mutants can be rescued by inducing the expression of a functional CDS1 or CDS2 gene |
739305 |
| 2.7.7.41 | more |
generation of a T-DNA insertion (in the 5' untranslated region) mutant of CDS2, the cds1cds2 double mutant is seedling lethal, phenotypes, overview. The seedling-lethal phenotype of cds1cds2 double mutants can be rescued by inducing the expression of a functional CDS1 or CDS2 gene |
739305 |
| 2.7.7.41 | more |
the cdsA-inactivated PAL mutant strain lacks phycobilisomes |
691056 |
