EC Number   |
Protein Variants |
Reference |
|---|
    2.7.4.2 | A293T |
site-directed mutagenesis, structure comparison with the wild-type enzyme |
759656 |
| 2.7.4.2 | D23N |
site-directed mutagenesis, the mutant shows highly reduced activity in both forward and reverse reactions compared to the wild-type enzyme |
672134 |
| 2.7.4.2 | K101M |
site-directed mutagenesis, structure comparison with the wild-type enzyme |
759656 |
| 2.7.4.2 | K101R |
site-directed mutagenesis, structure comparison with the wild-type enzyme |
759656 |
| 2.7.4.2 | K17M |
site-directed mutagenesis, the mutant shows reduced activity in both forward and reverse reactions compared to the wild-type enzyme |
672134 |
| 2.7.4.2 | K19M |
site-directed mutagenesis, the mutant shows highly reduced activity in both forward and reverse reactions compared to the wild-type enzyme |
672134 |
| 2.7.4.2 | K22M |
site-directed mutagenesis, the mutant shows a 10000fold reduced activity in both forward and reverse reactions compared to the wild-type enzyme, almost inactive mutant |
672134 |
| 2.7.4.2 | K48M |
mutant exhibits diminished Vmax values in both reaction directions with only slight Km perturbations |
672221 |
| 2.7.4.2 | K48M |
site-directed mutagenesis, the mutant shows altered kinetics and reduced activity in both forward and reverse reactions compared to the wild-type enzyme |
672221 |
| 2.7.4.2 | K69M |
mutant exhibits diminished Vmax values in both reaction directions with only slight Km perturbations |
672221 |
