EC Number   |
Protein Variants |
Reference |
|---|
    2.7.4.14 | E448G |
site-directed mutagenesis |
693063 |
| 2.7.4.14 | G21A |
mutant enzyme is degraded during the purification phase |
645158 |
| 2.7.4.14 | G22A |
mutant enzyme with decreased turnover-number/KmATP value. Turnover-number is 59% of that of the wild-type enzyme |
645158 |
| 2.7.4.14 | G24A |
mutant enzyme with decreased turnover-number/KmATP value. Turnover-number is 48% of that of the wild-type enzyme |
645158 |
| 2.7.4.14 | G26A |
mutant enzyme with decreased turnover-number/KmATP value |
645158 |
| 2.7.4.14 | G27R |
mutant enzyme is degraded during the purification phase. Turnover-number is 45% of that of the wild-type enzyme |
645158 |
| 2.7.4.14 | K27E |
mutant enzyme with 2600fold decreased turnover-number/KmATP value. Turnover-number is 21% of that of the wild-type enzyme |
645158 |
| 2.7.4.14 | K27M |
mutant enzyme with 1000fold decreased turnover-number/KmATP value. Turnover-number is 22% of that of the wild-type enzyme |
645158 |
| 2.7.4.14 | more |
construction of a UMP-CMPK2DELTA21 mutant lacking the mitochondrial targeting sequence |
693063 |
| 2.7.4.14 | more |
determination and analysis of 28 polymorphisms in DCK/CMPK enzymes, genotyping with humans of different ethnic origins, overview. Variant allozyme enzyme activities range from 32 to 105% of the wild-type enzyme for DCK and from 78 to 112% of wild-type enzyme for CMPK, with no significant differences in apparent Km values for either enzyme except for a DCK Val24/Ser122 double variant allozyme, overview |
692040 |
