EC Number   |
Protein Variants |
Reference |
|---|
    2.7.1.25 | C36A/C69A |
the mutant is not inhibited by oxidized glutathione and shows activity reduced to 71% |
739628 |
| 2.7.1.25 | C541A |
the mutant shows reduced activity compared to the wild type enzyme |
739408 |
| 2.7.1.25 | C549A |
the mutant shows increased activity compared to the wild type enzyme |
739408 |
| 2.7.1.25 | C556S |
inactive |
739408 |
| 2.7.1.25 | C86A/C119A |
the mutant is kinetically similar to the reduced wild type enzyme |
723657 |
| 2.7.1.25 | D136A |
the mutant displays drastically reduced affinity for adenosine 5'-phosphosulfate compared to the wild type enzyme |
722775 |
| 2.7.1.25 | D136N |
the mutant displays drastically reduced affinity for adenosine 5'-phosphosulfate compared to the wild type enzyme |
722775 |
| 2.7.1.25 | D87A |
almost complete loss of activity |
662177 |
| 2.7.1.25 | D87E |
80% loss of activity |
662177 |
| 2.7.1.25 | D87R |
almost complete loss of activity |
662177 |
