EC Number |
Protein Variants |
Reference |
---|
2.7.1.22 | D100A |
NRK2-D100A mutant protein does not accumulate appreciably, indicating that the mutant protein might be unstable |
759830 |
2.7.1.22 | D138A |
mutation has minor effects on catalysis |
682879 |
2.7.1.22 | D36A |
mutation abolishes activity |
682879 |
2.7.1.22 | D56A |
mutation abolishes activity |
682879 |
2.7.1.22 | E98A |
NRK1-E98A mutant protein does not accumulate appreciably, indicating that the mutant protein might be unstable |
759830 |
2.7.1.22 | K16A |
mutation abolishes activity |
682879 |
2.7.1.22 | more |
analysis of mutant strains for activities/functions of enzyme domains, reduced activity of class I mutants, overview |
659066 |
2.7.1.22 | more |
generation of H6PDKO/NRK2 double KO mice. H6PDKO/NRK2 double KO mice do not display an exaggerated timing or severity of myopathy or overt change in mitochondrial metabolism despite depression of NAD+ availability. Metabolome analysis |
-, 760203 |
2.7.1.22 | more |
generation of NRK2 knockout (KO) mice |
-, 758846 |