EC Number   |
Protein Variants |
Reference |
|---|
   2.7.1.158 | C162Y |
inactive |
738742 |
| 2.7.1.158 | D333A |
kinase dead mutant of Asp1 |
723173 |
| 2.7.1.158 | D368A |
inactive |
738589 |
| 2.7.1.158 | D368A |
site-directed mutagenesis, mutant IPK1D368A shows loss of kinase activity in vitro |
762144 |
| 2.7.1.158 | D437A |
site-directed mutagenesis, the mutant enzyme shows highly reduced activity |
761460 |
| 2.7.1.158 | D439A |
site-directed mutagenesis, nearly inactive mutant enzyme |
761460 |
| 2.7.1.158 | E82C/S142C |
the mutant exhibits a dithiothreitol-sensitive 5fold increase in kcat for 3,4,5,6-inositol tetrakisphosphate compared to the wild type enzyme |
738602 |
| 2.7.1.158 | H196A |
the mutant shows reduced activity compared to the wild type enzyme |
738589 |
| 2.7.1.158 | H397A |
phosphatase dead mutant of Asp1 |
723173 |
| 2.7.1.158 | K138A |
site-directed mutagenesis, the mutant enzyme shows highly reduced activity |
761460 |
