EC Number |
Protein Variants |
Reference |
---|
2.6.1.57 | K258A |
pKa of the Schiff base formed between the coenzyme pyridoxal 5'-phosphate and Lys258 increases by 3.6 units |
636673 |
2.6.1.57 | more |
construction of a DELTAaro9 knockout strain, also of a double mutant with aro8, overview |
-, 759287 |
2.6.1.57 | more |
construction of a DELTAyer152C knockout strain, also of a double mutant with aro8, overview |
-, 759287 |
2.6.1.57 | more |
construction of several DELTAaro8 knockout strains, also double mutants with aro9 and yer152C, genotypes, overview |
-, 759287 |
2.6.1.57 | more |
deletion of enzyme plus branched chain amino acid transaminase, strong reduction of growth of organism in milk. Strong reduction in degradation of L-isoleucine, L-valine, L-leucine, L-methionine, L-phenylalanine, L-tryptophan |
660743 |
2.6.1.57 | nutrition |
enzyme and branched chain amino acid transaminase are essential for conversion of aromatic and branched-chain amino acids to aroma compounds in the cheese model and also play a major role in the formation of volatile sulfur compounds from methionine |
661888 |
2.6.1.57 | R292A |
same pKa value as wild-type |
636661 |
2.6.1.57 | R292A |
very low activity with aspartate, 5-10fold increase in Km for aromatic amino acids |
636663 |
2.6.1.57 | R292K |
very low activity with aspartate, 10-100fold increase in Km for aromatic amino acids |
636663 |
2.6.1.57 | R292L |
- |
636673 |