EC Number   |
Protein Variants |
Reference |
|---|
    2.5.1.90 | A76Y |
main product is C20 |
704411 |
| 2.5.1.90 | A76Y |
mutant produces only C20 cores instead of the C40 core of octaprenyl diphosphate |
707469 |
| 2.5.1.90 | A76Y/S77F |
main product is C20 |
704411 |
| 2.5.1.90 | A76Y/S77F |
mutant produces only C20 cores instead of the C40 core of octaprenyl diphosphate. The A76Y/S77F mutant synthesizes a larger amount of C20 than the A76Y mutant |
707469 |
| 2.5.1.90 | A79Y |
no activity. Cells harboring wild-type ispB and the A79Y mutant produce mainly ubiquinone-6, although the activity of the enzyme with the A79Y mutation is completely abolished. Although the A79Y mutant is functionally inactive, it can regulate activity upon forming a heterodimer with wild-type IspB, and this dimer formation is important for the determination of the isoprenoid chain length |
637969 |
| 2.5.1.90 | D211A |
0.37% of wild-type activity |
721664 |
| 2.5.1.90 | D212A |
0.091% of wild-type activity |
721664 |
| 2.5.1.90 | D215A |
0.43% of wild-type activity |
721664 |
| 2.5.1.90 | D84A |
0.006% of wild-type activity |
721664 |
| 2.5.1.90 | D85A |
0.016% of wild-type activity |
721664 |
