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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
2.5.1.56
A506G/G420A
increase in specific activity
-
,
759716
2.5.1.56
C182A
no activity
671716
2.5.1.56
C182S
no activity
671716
2.5.1.56
C914T
decrease in specific activity
-
,
759716
2.5.1.56
C914T/G1018A
no significant change in specific activity
-
,
759716
2.5.1.56
E134A
site-directed mutagenesis
-
,
739614
2.5.1.56
E282A
site-directed mutagenesis
-
,
739614
2.5.1.56
E282A/T285A
site-directed mutagenesis
-
,
739614
2.5.1.56
G1018A
no significant change in specific activity
759716
2.5.1.56
G133V
naturally occuring mutation of the enzyme causing impaired enzyme activity and the enzyme-deficiency phenotype
739153
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