EC Number   |
Protein Variants |
Reference |
|---|
    2.5.1.39 | D191A |
mutant shows no 3-geranylgeranyl-4-hydroxybenzoate formation, mutant shows some residual hydrolysis activity |
703208 |
| 2.5.1.39 | D195A |
mutant shows no 3-geranylgeranyl-4-hydroxybenzoate formation, mutant shows some residual hydrolysis activity |
703208 |
| 2.5.1.39 | D198A |
mutation enhances the expression of 1,4-dihydroxy-2-naphthoic acid octaprenyltransferase (MenA), which increases menaquinone production by 130.0% |
760056 |
| 2.5.1.39 | D71A |
mutant shows no 3-geranylgeranyl-4-hydroxybenzoate formation, mutant shows some residual hydrolysis activity |
703208 |
| 2.5.1.39 | D75A |
mutant shows no 3-geranylgeranyl-4-hydroxybenzoate formation, mutant shows some residual hydrolysis activity |
703208 |
| 2.5.1.39 | D76A |
mutation enhances the expression of 1,4-dihydroxy-2-naphthoic acid octaprenyltransferase (MenA), which increases menaquinone production by 87.9% |
760056 |
| 2.5.1.39 | G68A |
mutation has no influence on expression of 1,4-dihydroxy-2-naphthoic acid octaprenyltransferase (MenA) |
760056 |
| 2.5.1.39 | K81A |
mutation enhances the expression of 1,4-dihydroxy-2-naphthoic acid octaprenyltransferase (MenA), which increases menaquinone production by 96.2% |
760056 |
| 2.5.1.39 | L139A |
mutation enhances the expression of 1,4-dihydroxy-2-naphthoic acid octaprenyltransferase (MenA), which increases menaquinone production by 109.7% |
760056 |
| 2.5.1.39 | more |
CoQ biosynthesis in yeast null mutant cells can be rescued with expression of the human enzyme at a lower rate compared to cells rescued with the yeast enzyme |
657846 |
