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Results 1 - 9 of 9
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26C576A 187% of wild type activity 489889
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26H617A complete loss of activity 489889
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26more deletion of C-terminal 5 amino acids, inactive enzyme 489889
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26more generation of gene Agps knockout mice, phenotype, overview -, 739078
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26more generation of homo- and heterozygous APP knock-out mice, APP-/-, APP+/-, and mice expressing a truncated amyloid precursor protein, APP, the construct lacks the last 15 amino acids, APPDELTA/DELTA, that includes the presumably critical YENPTY motif, where adaptor proteins like Fe65 and X11 are proposed to bind through their phosphotyrosine-binding domains and which are responsible for nuclear targeting of APP intracellular domain 723024
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26more lentivirus-shRNA mediated AGPS silencing in Hep-G2/ADM and U-87MG/DDP cancer cells 737578
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26R419H inactive enzyme 489895
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26R419K 1% of wild type activity 489889
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26S367A 4% of wild type activity 489889
Results 1 - 9 of 9
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