EC Number |
Protein Variants |
Reference |
---|
2.4.2.31 | C11S |
the mutation results in an auto-ADP-ribosylation comparable to the wild type enzyme |
736078 |
2.4.2.31 | C128S |
the mutant does not have a stable Fe-S cluster and reduced auto-ADP-ribosylation activity |
736078 |
2.4.2.31 | C130S |
the mutation results in an auto-ADP-ribosylation comparable to the wild type enzyme |
736078 |
2.4.2.31 | C201F |
mutant enzyme of RT6.1, mutant enzyme loses thiol-dependency |
638125 |
2.4.2.31 | C67S |
the mutant does not have a stable Fe-S cluster and reduced auto-ADP-ribosylation activity |
736078 |
2.4.2.31 | C80S |
mutant enzyme of RT6.1 remains thiol-dependent |
638125 |
2.4.2.31 | DELTA278-322 |
a deletion mutant lacking the region encompassing the putative transmembrane domain (aminoacids 278-322) shows a diffuse, cytosolic localization compared with full length ARTD15 |
723565 |
2.4.2.31 | E109D |
the mutation results in an auto-ADP-ribosylation comparable to the wild type enzyme |
736078 |
2.4.2.31 | E111D |
catalytic activity close to wild-type |
722703 |
2.4.2.31 | E111D |
the mutation results in an auto-ADP-ribosylation comparable to the wild type enzyme |
736078 |