EC Number   |
Protein Variants |
Reference |
|---|
   2.4.1.255 | C835A |
the mutation has no effect compared with wild type enzyme |
723250 |
| 2.4.1.255 | C836S |
site-directed mutagenesis to target potentially important amino acid residues within the conserved catalytic domain CD II, 10% activity compared to wild type |
659497 |
| 2.4.1.255 | C839S |
site-directed mutagenesis to target potentially important amino acid residues within the conserved catalytic domain CD II, less than 1% activity compared to wild type |
659497 |
| 2.4.1.255 | C911A |
active site mutant |
723250 |
| 2.4.1.255 | C917A |
active site mutant |
723250 |
| 2.4.1.255 | C917A |
mutant efficiently transfers diazirine-modified GlcNDAz and has altered substrate specificity, preferring to transfer GlcNDAz rather than GlcNAc to protein substrates |
736484 |
| 2.4.1.255 | D368A |
activity is identical to wild-type enzyme |
759411 |
| 2.4.1.255 | D386A/D420A |
activity is 190% compared to wild-type enzyme |
759411 |
| 2.4.1.255 | D386A/D420A/D454A |
activity is 170% compared to wild-type enzyme |
759411 |
| 2.4.1.255 | D407A |
significant inhibitory effect on OGT enzyme activity, site-directed mutagenesis to target potentially important amino acid residues within the conserved catalytic domain CD I |
659497 |
