EC Number |
Protein Variants |
Reference |
---|
2.3.3.13 | D444A |
the mutant shows increased catalytic efficiency compared to the wild type enzyme |
735592 |
2.3.3.13 | D444R |
the mutant shows increased catalytic efficiency compared to the wild type enzyme |
735592 |
2.3.3.13 | D444Y |
the mutant shows decreased catalytic efficiency compared to the wild type enzyme |
735592 |
2.3.3.13 | D546A |
the enzyme shows wild type activity but is not inhibited by L-leucine |
718698 |
2.3.3.13 | D563A |
the enzyme is more sensitive to L-leucine inhibition compared to the wild type enzyme |
718935 |
2.3.3.13 | D563N |
the enzyme is more sensitive to L-leucine inhibition compared to the wild type enzyme |
718935 |
2.3.3.13 | D563N |
the enzyme shows wild type activity but is not inhibited by L-leucine |
718698 |
2.3.3.13 | D564A |
the enzyme is less sensitive to L-leucine inhibition compared to the wild type enzyme |
718935 |
2.3.3.13 | D578Y |
release of leucine feedback inhibition and hyperproduction of isoamyl alcohol in mutant cells. Mutant shows resistance to 5,5,5-trifluoro-DL-leucine |
672656 |
2.3.3.13 | D81A |
the mutant shows strongly decreased activity compared to the wild type enzyme |
735710 |