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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3D546A MprF(-8) mutant, replacement results in slightly reduced production of lysyl-phosphatidylglycerol, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3D731A MprF(-8) mutant, exchange leads to complete abrogation of lysyl-phosphatidylglycerol production, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3E624A MprF(-8) mutant, exchange leads to complete abrogation of lysyl-phosphatidylglycerol production, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3E685A MprF(-8) mutant, replacement results in strongly reduced production of lysyl-phosphatidylglycerol, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3I420N naturally occuring single nucleotide polymorphism (SNP) that does not alter daptomycin resistance and the lysyl-phosphatidylglycerol synthesizing activity 757555
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3I701T naturally occuring mutation in gene lysX, involved in Bejing genotype, the Ile701Thr mutation can affect the protein function -, 758524
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3K547A MprF(-8) mutant, exchange leads to complete abrogation of lysyl-phosphatidylglycerol production, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3K621A MprF(-8) mutant, exchange leads to complete abrogation of lysyl-phosphatidylglycerol production, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3K806A MprF(-8) mutant, exchange leads to complete abrogation of lysyl-phosphatidylglycerol production, same result is obtained when the mutation is introduced into the full-length MprF protein 706463
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.3L826F naturally occuring single nucleotide polymorphism (SNP) that does not alter daptomycin resistance and the lysyl-phosphatidylglycerol synthesizing activity 757555
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