EC Number   |
Protein Variants |
Reference |
|---|
    2.3.1.57 | D93N |
site-directed mutagenesis, the mutation affects both substrate binding and catalysis without changing the pH dependence of the enzyme |
702246 |
| 2.3.1.57 | E152Q |
mutation disrupts binding of stabilizing N1,N12-bis(ethyl)spermine to enzyme |
487268 |
| 2.3.1.57 | E170Stop |
mutation stabilizes enzyme, due to the lack of ubiquinated complexes |
487268 |
| 2.3.1.57 | E171Q |
mutation results in a marked stabilization of enzyme, due to the lack of formation of high-molecular-mass complexes with ubiquitin |
487268 |
| 2.3.1.57 | E172A |
mutation stabilizes enzyme, due to the lack of ubiquinated complexes |
487268 |
| 2.3.1.57 | E173A |
mutation stabilizes enzyme, due to the lack of ubiquinated complexes |
487268 |
| 2.3.1.57 | E33Q |
the mutant shows greatly reduced enzyme activity compared to the wild type enzyme |
-, 756930 |
| 2.3.1.57 | E34Q |
inactive |
756930 |
| 2.3.1.57 | E37Q |
inactive |
756930 |
| 2.3.1.57 | E41Q |
inactive |
756930 |
