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Results 1 - 10 of 10
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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 2.3.1.257D127A/E129A the mutant shows significantly decreased catalytic efficiency (1.6-18fold) compared to the wild type enzyme 741447
Display the reaction diagram Show all sequences 2.3.1.257E139Q inactive 741447
Display the reaction diagram Show all sequences 2.3.1.257more enzyme silencing by lentivirus-based shRNA sequences (NAA40-KD1 and NAA40-KD2) targeting two distinct sites of NAA40 mRNA in HCT-116, HT-29, SW-480, and SW-620 cells. Depletion of NAA40 impedes cell proliferation and results in morphological alterations, such as cellular rounding. NAA40 depletion impairs CRC xenograft tumor growth 756385
Display the reaction diagram Show all sequences 2.3.1.257T174A the mutant shows wild type catalytic efficiency 741447
Display the reaction diagram Show all sequences 2.3.1.257W90A the mutant exhibits markedly decreased catalytic efficiency (2.8fold) compared to the wild type enzyme 741447
Display the reaction diagram Show all sequences 2.3.1.257Y136A the mutant shows significantly decreased catalytic efficiency (1.6-1.8fold) compared to the wild type enzyme 741447
Display the reaction diagram Show all sequences 2.3.1.257Y136F the catalytic efficiency of the mutant is modestly affected compared to the wild type enzyme 741447
Display the reaction diagram Show all sequences 2.3.1.257Y138A the mutant shows significantly decreased catalytic efficiency (1.6-1.8fold) compared to the wild type enzyme 741447
Display the reaction diagram Show all sequences 2.3.1.257Y211A the mutant shows wild type catalytic efficiency 741447
Display the reaction diagram Show all sequences 2.3.1.257Y85A the mutant exhibits markedly decreased catalytic efficiency (5.8fold) compared to the wild type enzyme 741447
Results 1 - 10 of 10
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