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Protein Variants:
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EC Number
Protein Variants
Commentary
Reference
2.3.1.251
D84A
mutation does not alter protein function
734717
2.3.1.251
D84N
mutation does not alter protein function
734717
2.3.1.251
D86A
mutation does not alter protein function
734717
2.3.1.251
D86N
mutation does not alter protein function
734717
2.3.1.251
H35F
loss of catalytic activity
734717
2.3.1.251
H35N
loss of catalytic activity
734717
2.3.1.251
H45F
mutation does not alter protein function
734717
2.3.1.251
K91S
mutation leads to 2fold reduction in the protein stability by about 3.45 kcal/mol
733316
2.3.1.251
L57Q
mutation leads to destabilizization by about 3.5 kcal/mol
733316
2.3.1.251
Q57L
presence of Leu confers an added 2.2 kcal/mol stabilization
733316
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