EC Number |
Protein Variants |
Reference |
---|
2.3.1.199 | C223A |
the mutant enzyme lacking the acylation site is unable to carry out decarboxylation of malonyl-CoA even when oleic acid-CoA is present |
719400 |
2.3.1.199 | H391A |
the mutant enzyme lacking the acylation site is unable to carry out decarboxylation of malonyl-CoA even when oleic acid-CoA is present |
719400 |
2.3.1.199 | H391K |
the mutant shows very low condensation activity |
719400 |
2.3.1.199 | H391Q |
the mutant shows low condensation activity (25% activity compared to the wild type enzyme) |
719400 |
2.3.1.199 | more |
strains containing mutant forms of elo1 with deletion of fatty acid synthase 2 cannot elongate myristic acid but palmitic acid |
-, 719787 |
2.3.1.199 | N424D |
the mutant shows low condensation activity |
719400 |
2.3.1.199 | N424H |
the mutant enzyme lacking the acylation site is unable to carry out decarboxylation of malonyl-CoA even when oleic acid-CoA is present |
719400 |
2.3.1.199 | S282A |
the mutant shows reduced activity with 20:1DELTA11 and erucic acid-CoA as substrates compared to the wild type enzyme |
719484 |
2.3.1.199 | S282C |
the mutant shows increased activity with 20:1DELTA11 and erucic acid-CoA as substrates compared to the wild type enzyme |
719484 |
2.3.1.199 | S282G |
the mutant shows wild type activity with 20:1DELTA11 and erucic acid-CoA as substrates |
719484 |