EC Number |
Protein Variants |
Reference |
---|
2.3.1.122 | L130S |
leucine at position 130 of Mycobacterium leprae FbpA limits access of mycolate-containing glycolipid substrates to their binding site. Mutant L130S exhibits an enhanced mycosyltransferase activity compared to wild-type while the ability to transfer the unbranched acyl chain is unchanged. Km (substrate: short-chain trehalose monomycolate): 0.043 mM, sharply decreased compared to wild-type |
702229 |
2.3.1.122 | more |
deletion mutant of enzyme genes cmytA and cmytB. Double mutant fails to grow at 34°C. It exhibits a growth defect and forms segmentation-defective cells at 30°C. Double mutant elaborates 60% less cell-wall-bound corynomycolates and produces less crystalline surface layer proteins than wild-type |
659891 |
2.3.1.122 | S130L |
mutant S130L of Mycobacterium avium exhibits a reduced mycosyltransferase activity compared to wild-type |
702229 |
2.3.1.122 | S148A |
mutant lacks observable transesterase activity but exhibits hydrolase activity at a lower level than that of wild-type |
-, 757211 |
2.3.1.122 | S148T |
mutant lacks observable transesterase activity but exhibits hydrolase activity at a lower level than that of wild-type |
-, 757211 |
2.3.1.122 | S189V |
mutation in putative catalytic serine, complete loss of mycoloyltransferase activity |
-, 736359 |