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EC Number	Protein Variants	Commentary	Reference
2.3.1.108	C120A	complete loss of activity	736637
2.3.1.108	D157A	complete loss of activity	736637
2.3.1.108	D157N	complete loss of activity	736637
2.3.1.108	D157N	inactive mutant	720907
2.3.1.108	D157N	site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme	719403
2.3.1.108	F105A	complete loss of activity	736637
2.3.1.108	F105A	mutation in highly conserved surface patches adjacent to the substrate-binding groove, pronounced effetc on catalytic activity	736637
2.3.1.108	F183A	complete loss of activity	736637
2.3.1.108	F183A	mutation in highly conserved surface patches adjacent to the substrate-binding groove, pronounced effetc on catalytic activity	736637
2.3.1.108	F186A	mutation in highly conserved surface patches adjacent to the substrate-binding groove, pronounced effetc on catalytic activity	736637

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Release 2023.1 (January 2023)