Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Protein Variants

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 8 of 8
EC Number Protein Variants Commentary Reference
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354G951S the mutation displays benomyl resistance equivalent to that caused by enzyme deletion. The mutation affects Mad2 localization in dividing cells -, 753744
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354more HMT activity of set1 null mutant strain is significantly reduced compared with the wild-type strain 676066
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354more set1 null mutant, heterozygous mutant, and reinsertion strains, HMT activity of the set1 null mutant strain is significantly reduced compared with strain CAI12, heterozygous mutant and reinsertion strains, disruption of SET1 results in complete loss of methylation of histone 3 at lysine residue 4, hyperfilamentous growth under embedded conditions, less negative cell surface charges and diminished adherence to epithelial cells, effects reversed upon gene reinsertion at a disrupted locus -, 676066
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354more the removal of the WD40 domain-containing subunits Swd1 and Swd3 of the complex of proteins associated with Set1, which contribute to the stability of Set1, leads to a loss of Set1 protein and consequently a complete loss of histone H3(K4) methylation 720034
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354S289N the PRDM7 mutant loses the dimethylated substrate specificity and instead gains the ability to methylate H3K36 similar to, but less efficiently than its evolutionary predecessor PRDM9 754135
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354S289N/S312W/S357Y the PRDM7 mutant regains the substrate specificities and catalytic activities similar to its evolutionary predecessor PRDM9, including the ability to efficiently methylate histone H3 lysine 36 754135
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354S312W the PRDM7 mutant loses the dimethylated substrate specificity and instead gains the ability to methylate H3K36 similar to, but less efficiently than its evolutionary predecessor PRDM9 754135
Show all pathways known for 2.1.1.354Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.354S357Y the PRDM7 mutant regains the substrate specificities and catalytic activities similar to its evolutionary predecessor PRDM9, including the ability to efficiently methylate histone H3 lysine 36 754135
Results 1 - 8 of 8