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Results 1 - 6 of 6
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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 2.1.1.308C282A the mutant enzyme is not able to produce the catalytic [4Fe-4S]+1 cluster 729108
Display the reaction diagram Show all sequences 2.1.1.308C282A/C286A/C289A the triple-variant is very unstable and precipitated during purification and subsequent manipulation for experiments. It completely lacks the [4Fe-4S]+1 cluster 729108
Display the reaction diagram Show all sequences 2.1.1.308C286A the mutant enzyme is not able to produce the catalytic [4Fe-4S]+1 cluster 729108
Display the reaction diagram Show all sequences 2.1.1.308C289A the mutant enzyme is not able to produce the catalytic [4Fe-4S]+1 cluster 729108
Display the reaction diagram Show all sequences 2.1.1.308more a mutant of Streptomyces wedmorensis (A16), defective in the biosynthesis of cobalamin produces fosfomycin only in the presence of hydroxocobalamin. Incorporation of [14CH3]methylcobalamin into fosfomycin by the mutant A16 704215, 705861
Display the reaction diagram Show all sequences 2.1.1.308more site-directed mutagenesis of the cysteine residues in the radical SAM CxxxCxxC motif indicates that each residue is essential for functional cluster formation 729108
Results 1 - 6 of 6
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