EC Number   |
Protein Variants |
Reference |
|---|
   1.8.99.B1 | C146S |
not active in the insulin reductase assay, oxidation of the dithiol peptide NRCSQGSCWN is reduced |
661641 |
| 1.8.99.B1 | C148S |
mutant enzyme exhibits a lower activity compared to wild-type enzyme |
725698 |
| 1.8.99.B1 | C155S/C158S |
with insulin as substrate the enzyme is completely inactive |
-, 701047 |
| 1.8.99.B1 | C173S/C178S |
with insulin as substrate the enzyme shows lower activity than wild-type enzyme |
-, 701047 |
| 1.8.99.B1 | C34S |
mutant enzyme retains nearly wild-type activity |
725698 |
| 1.8.99.B1 | C34S/C148S |
mutant enzyme shows no activity |
725698 |
| 1.8.99.B1 | C35S |
active in the insulin reductase assay, oxidation of the dithiol peptide NRCSQGSCWN is comparable to wild-type enzyme |
661641 |
| 1.8.99.B1 | C35S/C146S |
not active in the insulin reductase assay, no oxidation of the dithiol peptide NRCSQGSCWN |
661641 |
| 1.8.99.B1 | C41S/C44S |
with insulin as substrate the enzyme shows lower activity than wild-type enzyme |
-, 701047 |
