EC Number |
Protein Variants |
Reference |
---|
1.7.2.4 | C165G |
Cys165 is not available for Cu cooordination |
394527 |
1.7.2.4 | C165G |
retaines catalytic activity |
394527 |
1.7.2.4 | C622D |
no activity, distorted CuA-centre |
394518 |
1.7.2.4 | D576A |
the mutant shows specific activity comparable to the wild type enzyme |
764981 |
1.7.2.4 | D576A/S550A |
the mutant shows decreased specific activity compared to the wild type enzyme |
764981 |
1.7.2.4 | E296Q |
mutation near T1 copper site, similar biochemical and spectroscopic properties to those of the wild type |
724958 |
1.7.2.4 | H583A |
inactive |
764981 |
1.7.2.4 | H583D |
the oxidation rate of the CuA site in the mutant enzyme is much lower than that of wild type |
764981 |
1.7.2.4 | H583E |
the oxidation rate of the CuA site in the mutant enzyme is much lower than that of wild type |
764981 |
1.7.2.4 | H583F |
inactive |
764981 |