EC Number   |
Protein Variants |
Reference |
|---|
  1.3.99.41 | E435A |
the mutation completely abolishes the activity of the enzyme |
765397 |
| 1.3.99.41 | F195A |
the mutation almost completely abolishes the activity of the enzyme to 0.4% of wild type activity |
765397 |
| 1.3.99.41 | F287A |
the mutant with 76.3% of wild type activity shows significantly increased Km to 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | H280A |
the mutation severely reduces the activity of the enzyme to 18.2%, but does not affect its Km value to 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | K223A |
the mutation severely reduces the activity of the enzyme to 9.4%, but does not affect its Km value to 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | K281A |
the mutation severely reduces the activity of the enzyme to 54.5%, but does not affect its Km value to 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | M161A |
the mutation significantly decreases the activity of the enzyme to 37.5% and does not affect its Km value to FAD or 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | R284A |
the mutant with 97.2% of wild type activity shows significantly increased Km to 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | R448A |
the mutant with 44.9% of wild type activity shows significantly increased Km for 3-(methylsulfanyl)propanoyl-CoA |
765397 |
| 1.3.99.41 | S197A |
the mutation significantly decreases the activity of the enzyme to 3.6% and increases its Km value to FAD |
765397 |
