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Results 1 - 5 of 5
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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.B13H296G inactive mutant enzyme, shows no reduction of polyprenol 719256
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.B13H321L site-directed mutagenesis, the mutant shows 47% of wild-type reductase activity -, 746028
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.B13H336L site-directed mutagenesis, the mutant shows 45% of wild-type reductase activity -, 746028
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.B13more PPRD2 mutants with His321 or His336, corresponding to His296 or His309 in human hSRD5A3, substituted by Leu are employed to complement the yeast dfg10DELTA mutant. Construction of two heterozygous T-DNA PPRD2 insertion lines, pprd2-1 (SALK_113221C) and pprd2-2 (SALK_006421), PPRD2 deficiency is lethal in Arabidopsis thaliana due to male sterility, PPRD2 knockout plants are not viable. For the pprd2 homozygous mutants, consistently with their Dol deficiency, defects in N-glycosylation are accompanied by degradation of some proteins, e.g., SKU5 -, 746028
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.B13more total loss of activity of the putative C-terminally truncated PPRD1 proteins encoded by PPRD1-INT3 and PPRD1-INT4 -, 746028
Results 1 - 5 of 5
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