EC Number   |
Protein Variants |
Reference |
|---|
    1.3.1.98 | E275K |
strong decrease in enzyme activity, thinner cell walls than wild type strain |
655618 |
| 1.3.1.98 | E296A |
site-directed mutagenesis, highly reduced activity compared to the wild-type enzyme, no complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
| 1.3.1.98 | G251D |
strong decrease in enzyme activity, thinner cell walls than wild type strain |
655618 |
| 1.3.1.98 | G67A |
site-directed mutagenesis, functional complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
| 1.3.1.98 | G69A |
site-directed mutagenesis, functional complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
| 1.3.1.98 | G78D |
strong decrease in enzyme activity, thinner cell walls than wild type strain |
655618 |
| 1.3.1.98 | H259A |
site-directed mutagenesis, highly reduced activity compared to the wild-type enzyme, no complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
| 1.3.1.98 | more |
construction of a murB null mutant strain UHM350, introduction of PpetE-murB (pPJAV329) into the murB mutant in the presence of copper is sufficient for complete segregation of the murB insertion and created a viable strain UHM350, which displays a growth defect and spontaneously lyses if not passaged every 2 weeks once a sufficient density is reached during plate-based culture containing copper. The pattern of functional heterocysts and average filament lengths is altered and impaired compared to the wild-type |
-, 745220 |
| 1.3.1.98 | N71A |
site-directed mutagenesis, highly reduced activity compared to the wild-type enzyme, no complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
| 1.3.1.98 | R176A |
site-directed mutagenesis, highly reduced activity compared to the wild-type enzyme, no complementation of murB-deficient, temperature-sensitive Staphylcoccus aureus mutant strain TS2901 |
669466 |
