EC Number |
Protein Variants |
Reference |
---|
1.3.1.10 | A95V |
the mutant correlates with resistance to diphenyl ethers and causes a significant reduction in the affinity of the inhibitors for the enzyme |
685233 |
1.3.1.10 | F204S |
inactive, the mutant correlates with resistance to diphenyl ethers and causes a significant reduction in the affinity of the inhibitors for the enzyme |
685233 |
1.3.1.10 | G93S |
leads to diazaborine resistance |
390503, 390506, 390507 |
1.3.1.10 | G93V |
leads to triclosan resistance |
390504 |
1.3.1.10 | I193S |
the mutant correlates with resistance to diphenyl ethers and causes a significant reduction in the affinity of the inhibitors for the enzyme |
685233 |
1.3.1.10 | K41N |
strongly decreased activity for NADPH and increased activity with NADH |
685233 |
1.3.1.10 | M99T |
the mutant is resistant toward inhibition by AFN-1252 |
-, 740716 |
1.3.1.10 | more |
deletion of the loop from Tyr96 to Val101 via site-directed mutagenesis results in the loss of triclosan resistance. The mutant FabL2 retains its enoyl-acyl carrier protein reductase activity |
762612 |
1.3.1.10 | more |
the ygaA knockout is 250fold more sensitive to the inhibitor triclosan |
-, 390505 |
1.3.1.10 | R40Q |
strongly decreased activity for NADPH and increased activity with NADH |
685233 |