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EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 1.2.1.107H176N the mutant shows a Km value 5times smaller than for the wild type enzyme while the Km value for arsenate is about 5times larger. The mutant has a significantly reduced thermal stability at 65°C. The half-life for thermal denaturation for the mutant holoenzyme is increased nearly 100fold over the corresponding value for the apoenzyme 761057
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