EC Number   |
Protein Variants |
Reference |
|---|
   1.14.99.63 | A205V |
mutation improves astaxanthin production |
748562 |
| 1.14.99.63 | A208V |
mutation improves astaxanthin production |
748562 |
| 1.14.99.63 | A215T |
mutation improves astaxanthin production |
748562 |
| 1.14.99.63 | D117A |
expression of a mutant carrying D117A results in the accumulation of echinenone as the predominant carotenoid. Partial inactivation of the CrtW ketolase leads to the production of the monoketolated intermediate |
746817 |
| 1.14.99.63 | F118A |
Escherichia coli cells expressing the partially active mutant enzyme accumulate adonixanthin as the dominant intermediate and produce less than 30% astaxanthin. When the mutant enzyme is expressed in the host harboring the beta-carotene biosynthetic cluster, the final product, canthaxanthin, is the predominant pigment |
746817 |
| 1.14.99.63 | F176A |
Escherichia coli cells expressing the partially active mutant enzyme accumulate adonixanthin as the dominant intermediate and produce less than 30% astaxanthin. When the mutant enzyme is expressed in the host harboring the beta-carotene biosynthetic cluster, the final product, canthaxanthin, is the predominant pigment |
746817 |
| 1.14.99.63 | F213L |
mutant enzyme shows high improvement for astaxanthin production and decreased activity for canthaxanthin production |
748562 |
| 1.14.99.63 | F213L |
mutation improves astaxanthin production |
748562 |
| 1.14.99.63 | F298Y |
improvement in canthaxanthin production |
742396 |
| 1.14.99.63 | H103A |
strains expressing the mutation do not produce ketolated products |
746817 |
