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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E113A site-directed mutagenesis, the mutant is completely inactive in deoxyhypusine hydroxylation, structure comparison to the wild-type enzyme 713728
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E116A site-directed mutagenesis, the mutant is completely inactive in deoxyhypusine hydroxylation, structure comparison to the wild-type enzyme 713728
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E116D site-directed mutagenesis, the mutant is completely inactive in deoxyhypusine hydroxylation, structure comparison to the wild-type enzyme 713728
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208A little reduction in iron content of enzyme, complete loss of activity 674548
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208A severe impairment in binding of substrate translation initiation factor 5A, complete loss of activity 674901
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208A site-directed mutagenesis, the mutant shows severely impairment in eIF5A(deoxyhypusine) binding 674901
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208D impairment in binding of substrate translation initiation factor 5A, retains some activity 674901
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208D site-directed mutagenesis, the mutant shows reduced but not fully abolished eIF5A(deoxyhypusine) binding 674901
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208N site-directed mutagenesis, the mutant shows severely impairment in eIF5A(deoxyhypusine) binding 674901
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.29E208Q site-directed mutagenesis, the mutant shows severely impairment in eIF5A(deoxyhypusine) binding 674901
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