EC Number   |
Protein Variants |
Reference |
|---|
   1.14.14.94 | V433M |
naturally occuring common genetic variant of the human CYP4F2 gene, the mutant has lower enzyme specific activity toward tocopherols, 42-66% of wild-type activity, but is without a significant effect on the metabolism of tocotrienols |
712833 |
| 1.14.14.94 | V433M |
the functional polymorphism in human Cyp4F2 decreases 20-hydroxyeicosatetraenoic acid production, but does not influence the omega-hydroxylation of leukotriene B4, screening and genotyping of African and European Americans, overview |
689399 |
| 1.14.14.94 | W12G |
naturally occuring common genetic variant of the human CYP4F2 gene, the mutant exhibits a greater enzyme specific activity compared to the wild-type enzyme for both tocopherols and tocotrienols, 230-275% of wild-type activity towards alpha, gamma, and delta-tocopherol and 350% of wild-type activity towards alpha, gamma, and delta-tocotrienol |
712833 |
| 1.14.14.94 | W12G |
the mutant enzyme activity is similar to the wild-type enzyme, screening and genotyping of African and European Americans, overview |
689399 |
| 1.14.14.94 | W12G/V433M |
the functional polymorphism in human Cyp4F2 decreases 20-hydroxyeicosatetraenoic acid production, but does not influence the omega-hydroxylation of leukotriene B4, screening and genotyping of African and European Americans, overview |
689399 |
