EC Number   |
Protein Variants |
Reference |
|---|
    1.14.13.9 | D184A |
site-directed mutagenesis, the mutation weakens the beta-sheet dimer interface of the enzyme |
764520 |
| 1.14.13.9 | E366A |
site-directed mutagenesis, mutation of a catalytic residue, inactive mutant |
765669 |
| 1.14.13.9 | E366Q |
2% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | E372A |
about 15% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | E372Q |
about 5% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | M367A |
2% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | M367L |
13% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | M373A |
no activity detected |
742478 |
| 1.14.13.9 | M373L |
about 60% of the enzyme activity compared with that of the wild-type enzyme |
742478 |
| 1.14.13.9 | more |
an inactive mutant lacks 162 nucleotides near the 3'-end of the mutant allele, the in-frame deletion results in loss of 54 amino acids leading to loss of enzyme activity and white eyes |
-, 658919 |
