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Results 1 - 10 of 35 > >>
EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69D191A site-directed mutagenesis, the mutant shows about 95%reduced activity with H3K9me3 compared to wild-type, and no activity with H3K36me3 754871
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69G133A site-directed mutagenesis, the mutation in the catalytic domain abrogates enzyme activity 753371
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69G138A site-directed mutagenesis, the mutation in the catalytic domain abrogates enzyme activity 753371
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69G165A site-directed mutagenesis, the mutation in the catalytic domain abrogates enzyme activity 753371
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69G170A site-directed mutagenesis, the mutation in the catalytic domain abrogates enzyme activity 753371
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69H195A construction of a mutant dKDM4A in which a conserved amino acid in the iron-binding site is mutated to alanine, the mutant dKDM4A has no demethylation activity on histones H3K36me3 and H3K36me2 700209
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69H195A site-directed mutagenesis 724813
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69H195A site-directed mutagenesis, mutation of an Fe2+ binding residue, abolishes demethylase activity of dJMJD2(1)/CG15835 754921
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69H235A catalytically deficient mutant -, 726071, 754922
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.69more construction of a P-element insertion mutant of dKDMA4, the mutant is homozygous viable, the P element insertion elevates the bulk level of histone H3K36me3 in mutant embryos. Overexpression of dKDM4A seems to only lead to demethylation of histone H3K36, since the level of histone H3K9me3 and H3K4me2 remains unchanged 700209
Results 1 - 10 of 35 > >>