EC Number |
Protein Variants |
Reference |
---|
1.11.1.25 | C185A |
active site mutant |
-, 765352 |
1.11.1.25 | C185A |
the mutant shows improved binding to plasminogen |
-, 765352 |
1.11.1.25 | C48S |
mutant enzyme does not exhibit activity |
-, 754106 |
1.11.1.25 | C51A |
mutation abolishes catalysis |
754065 |
1.11.1.25 | C76A |
mutant enzyme retains about 25% of the wild type peroxiredoxin activity |
754065 |
1.11.1.25 | K230A |
the mutant shows impaired binding to plasminogen |
-, 765352 |
1.11.1.25 | K230A/K244A |
the mutant shows impaired binding to plasminogen |
-, 765352 |
1.11.1.25 | K244A |
the mutant shows slightly impaired binding to plasminogen |
-, 765352 |
1.11.1.25 | R129Q |
inactive with H2O2 or tert-butyl hydroperoxide, catalyzes degradation of cumene hydroperoxide with low efficiency |
656927 |
1.11.1.25 | T48V |
inactive with H2O2 or tert-butyl hydroperoxide, catalyzes degradation of cumene hydroperoxide with low efficiency |
656927 |