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EC Number
Protein Variants
Commentary
Reference
1.1.1.218
C80S
change of cysteine to serine: significantly improved stability
-
,
286289
1.1.1.218
D47N
residue modified by site-directed mutagenesis, resulting in substantial loss of activity
-
,
286289
1.1.1.218
K76M
residue modified by site-directed mutagenesis, resulting in substantial loss of activity
-
,
286289
1.1.1.218
Y52F
F is incapable of acting as proton donor /aim: NAD+-dependent morphine dehydrogenase for biotransformation morphine-morphinone-hydromorphine, codeine-hydrocodone respectively (medically useful semisynthetic opiates)
-
,
286285
1.1.1.218
Y52F
residue modified by site-directed mutagenesis, resulting in substantial loss of activity
-
,
286289
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