EC Number   |
Protein Variants  |
Reference |
|---|
    4.3.3.6 | D26A/K83A/K151A |
no formation of an internal chromophore with characteristic absorbance at 320 nm during reaction (observed with wild type protein) |
724239 |
| 4.3.3.6 | D99A |
mutant of Pdx1 (pyridoxal 5'-phosphate synthase subunit), 5% of the pyridoxal 5'-phosphate synthase activity compared to wild-type enzyme with L-glutamine as N-donor, 17.2% of the glutaminase activity compared to wild-type enzyme |
714170 |
| 4.3.3.6 | DELTA 270-301 |
mainly monomer, Pdx2 activation, no pyridoxal 5'-phosphate synthesis |
724999 |
| 4.3.3.6 | DELTA 273-301 |
dodecamer, Pdx2 activation, no pyridoxal 5'-phosphate synthesis |
724999 |
| 4.3.3.6 | DELTA 279-301 |
dodecamer, Pdx2 activation, reduced pyridoxal 5'-phosphate synthesis |
724999 |
| 4.3.3.6 | DELTA 287-301 |
dodecamer, Pdx2 activation, precipitates upon addition of glyceraldehyd 3-phosphate |
724999 |
| 4.3.3.6 | DELTA 293-301 |
behaviour like DELTA 287-301 |
724999 |
| 4.3.3.6 | DELTA 295-301 |
behaviour like DELTA 287-301 |
724999 |
| 4.3.3.6 | E105D |
Pdx1 |
726269 |
| 4.3.3.6 | E116A |
activity as the wild-type protein |
724219 |
