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Results 1 - 10 of 53 > >>
EC Number
Amino acid exchange
Commentary
Reference
D26A/K83A/K151A
no formation of an internal chromophore with characteristic absorbance at 320 nm during reaction (observed with wild type protein)
D99A
mutant of Pdx1 (pyridoxal 5'-phosphate synthase subunit), 5% of the pyridoxal 5'-phosphate synthase activity compared to wild-type enzyme with L-glutamine as N-donor, 17.2% of the glutaminase activity compared to wild-type enzyme
DELTA 270-301
mainly monomer, Pdx2 activation, no pyridoxal 5'-phosphate synthesis
DELTA 273-301
dodecamer, Pdx2 activation, no pyridoxal 5'-phosphate synthesis
DELTA 279-301
dodecamer, Pdx2 activation, reduced pyridoxal 5'-phosphate synthesis
DELTA 287-301
dodecamer, Pdx2 activation, precipitates upon addition of glyceraldehyd 3-phosphate
DELTA 293-301
behaviour like DELTA 287-301
DELTA 295-301
behaviour like DELTA 287-301
E105D
Pdx1
E116A
activity as the wild-type protein
Results 1 - 10 of 53 > >>