EC Number   |
Protein Variants |
Reference |
|---|
   3.5.4.33 | D64E |
D64E abolishes the enzymatic activity of tadA in vitro, it does not detectably affect its activity in cells |
719356 |
| 3.5.4.33 | more |
deletion of the last 10 amino acids at the C terminus of TbADAT2 abolishes tRNA binding. In addition, single alanine replacements of a string of positively charged amino acids (KRKRK) lead to binding defects that correlate with losses in enzyme activity |
721030 |
| 3.5.4.33 | E92A/K216A/R217A/K218A/R219A |
inactive mutant enzyme |
721030 |
| 3.5.4.33 | F145A |
inactive mutant enzyme |
718839 |
| 3.5.4.33 | C136A/ADAT3 C291A |
inactive mutant enzyme, mutation in subunit ADAT2 |
719934 |
| 3.5.4.33 | C139A |
inactive mutant enzyme, mutation in subunit ADAT2 |
719934 |
| 3.5.4.33 | E92A |
inactive mutant enzyme, mutation in subunit ADAT2 |
719934 |
| 3.5.4.33 | H90A |
inactive mutant enzyme, mutation in subunit ADAT2 |
719934 |
| 3.5.4.33 | C291A |
inactive mutant enzyme, mutation in subunit ADAT3 |
719934 |
| 3.5.4.33 | C294A |
inactive mutant enzyme, mutation in subunit ADAT3 |
719934 |
