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EC Number
Protein Variants
Commentary
Reference
3.4.24.82
E362A
catalytically inactive
733990
3.4.24.82
E362A
inactive mutant enzyme with mutation of Glu to Ala at position 362
669206
3.4.24.82
E362Q
active site mutant, no aggrecanase activity, no autocatalytic cleavage
638962
3.4.24.82
E362Q
inactive mutant, single point mutation (G to C) leading to the amino acid change at residue 362 located within the catalytic domain of ADAMTS4
669205
3.4.24.82
E362Q
proteolytically inactive, but still activationg effect on neurite extension
697804
3.4.24.82
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the catalytic domain alone is enzymatically inactive
680792
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