EC Number   |
Protein Variants |
Reference  |
|---|
   3.4.22.71 | more |
marked changes in the specificity profile of SrtA are obtained by replacing the beta6/beta7 loop in SrtA with the corresponding domain from SrtB |
680881 |
| 3.4.22.71 | C221S |
the single residue mutation does not have noticeable effect on the secondary structure of the enzyme |
-, 718269 |
| 3.4.22.71 | C223A |
site-directed mutagenesis, inactive mutant |
732174 |
| 3.4.22.71 | D225A |
site-directed mutagenesis, the mutant exhibits nonspecific proteolytic activity |
732174 |
| 3.4.22.71 | H130A |
site-directed mutagenesis, inactive mutant |
732174 |
| 3.4.22.71 | R233A |
site-directed mutagenesis, inactive mutant |
732174 |
| 3.4.22.71 | C232S |
inactive |
-, 752669 |
| 3.4.22.71 | I182A |
the inhibitory effect of coptisine on mutants decreases in the order wild-type > R115A > I182A > N116A |
-, 754800 |
| 3.4.22.71 | N116A |
the inhibitory effect of coptisine on mutants decreases in the order wild-type > R115A > I182A > N116A |
-, 754800 |
| 3.4.22.71 | R115A |
the inhibitory effect of coptisine on mutants decreases in the order wild-type > R115A > I182A > N116A |
-, 754800 |
