EC Number   |
Protein Variants |
Reference  |
|---|
   3.4.22.49 | R1486A |
mutation fails to block autocatalytical cleavage |
638863 |
| 3.4.22.49 | R1506A |
mutation at autocatalytical cleavage site, mutant enzyme is still cleaved indicating the existence of a second cleavage site |
638863 |
| 3.4.22.49 | R1506A/R1486A |
mutation fails to block autocatalytical cleavage |
638863 |
| 3.4.22.49 | H1531A |
active site point mutation prevents Scc1 from being cleaved after binding |
638864 |
| 3.4.22.49 | C2029A |
no autoproteolytic cleavage, unable to cleave SCC1 |
638865 |
| 3.4.22.49 | S1126A |
cleaved autoproteolytically to the same degree as wild-type, shows similar SCC1 cleavage activity as wild-type |
638865 |
| 3.4.22.49 | C2029A |
- |
638869 |
| 3.4.22.49 | E1483R/R1486E |
autoproteolytically cleaved like wild-type |
638869 |
| 3.4.22.49 | E1503R/R1506E |
autoproteolytically cleaved like wild-type |
638869 |
| 3.4.22.49 | E1532R/R1535E |
autoproteolytically cleaved like wild-type |
638869 |
