Refine search

Search Engineering

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 24 > >>
EC Number
Protein Variants
Commentary
Reference
D132A
site directed mutagenesis
D132A
the mutant shows reduced activity compared to the wild type enzyme, the mutation has the most dramatic consequences on the protein stability as Tm decreases by 9C in comparison with the wild type protein, an increase in the specificity of the D132A variant for UMP over CMP and dCMP is observed
D132A
the substitution results in a moderate decrease in stability without significant changes in Km value for CMP and dCMP
D132H
site directed mutagenesis
D132H
the mutant shows reduced activity compared to the wild type enzyme
D132H
the substitution results in a moderate decrease in stability without significant changes in Km value for CMP and dCMP, the D132H variant does not introduce charge reversal, because His is calculated to be deprotonated
D132N
site directed mutagenesis
D132N
the mutant shows reduced activity compared to the wild type enzyme
D132N
the substitution results in a moderate decrease in stability without significant changes in Km value for CMP and dCMP
D132S
site directed mutagenesis
Results 1 - 10 of 24 > >>